Mironov, Sergej L.

Curriculum vitae

1970 - 1975
1975 - 1979

1979 - 1989

1989 - 1993
1993 - 1995
University Kiew, Natural Sciences
Dept. Quantum Chemistry, Inst. Phys. Chem, Kiew/PhD Student
PhD Thesis in Physical Chemistry:
Electron transport in 1- und 2-dimensionall Systems. Dr. rer. nat.
Dept. Gen. Physiol., Bogomoletz Inst. Physiology
Habilitation in Physiology:
Mechanisms of Ca2+ binding and transport in neurons
MPI für Psychiatrie, München
Univ. Salzburg, Guest professor
Dept. Neuro- und Sensory Physiology, Georg-August-Universität Göttingen

List of Publications

  1. Mironov SL, Skorova EY, Kügler S. 2011. Epac-mediated cAMP-signalling in the mouse model of Rett Syndrome. Neuropharmacology. 60: 869-77.
  2. Mironov SL, Skorova EY. 2011. Stimulation of bursting in pre-Bötzinger neurons by Epac through calcium release and modulation of TRPM4 and K-ATP channels. J Neurochem., 117: 295-308.
  3. Mironov SL. 2009. Complexity of mitochondrial dynamics in neurons and its control by ADP produced during synaptic activity. Int J Biochem Cell Biol. 41: 2005-2014.
  4. Mironov S, Skorova E, Hartelt N, Mironova L, Hasan M, Kügler S. 2009. Remodelling of the respiratory network in mouse model of Rett syndrome depends on BDNF-regulated slow calcium buffering. J Physiol. 587:2473-85.
  5. Mironov S, Skorova E, Taschenberger G, Nikolaev VO, Lohse MJ, Kügler S. 2009. Imaging cytoplasmic cAMP in mouse brainstem neurons. BMC Neuroscience 10: 29-38.
  6. Hartelt N, Skorova E, Manzke T, Suhr M, Mironova L, Kügler S, Mironov SL. 2008. Imaging of respiratory network topology in living brainstem slices. Mol Cell Neurosci. 37: 425-31.
  7. Mironov SL. 2008. Metabotropic glutamate receptors activate dendritic calcium waves and TRPM channels which drive rhythmic respiratory patterns in mice. J Physiol. 586: 2272-2291.
  8. Hartelt N, Skorova E, Manzke T, Suhr M, Mironova L, Kügler S, Mironov SL. 2008. Imaging of respiratory network topology in living brainstem slices. Mol Cell Neurosci. 37: 425-31.
  9. Mironova LA, Mironov SL. 2008. Approximate analytical time-dependent solutions to describe large-amplitude local calcium transients in the presence of buffers. Biophys J 94: 349-58.
  10. Mironov SL. 2007. ADP regulates movements of mitochondria in neurons. Biophys J. 92: 2944-52.
  11. Mironov SL, Langohr K. 2007. Modulation of synaptic and channel activities in the respiratory network of the mice by NO/cGMP signalling pathways. Brain Res. 1130: 73-82.
  12. Mironov SL, Symonchuk N. 2006. ER vesicles and mitochondria move and communicate at synapses. J Cell Sci. 119: 4926-34.
  13. Mironov SL. 2006. Spontaneous and evoked neuronal activities regulate movements of single neuronal mitochondria. Synapse. 59: 403-11.
  14. Mironov SL, Langohr K. 2005. Mechanisms of Na+ and Ca2+ influx into respiratory neurons during hypoxia. Neuropharmacology. 48: 1056-65.
  15. Mironov SL, Hartelt N, Ivannikov MV. 2005. Mitochondrial K(ATP) channels in respiratory neurons and their role in the hypoxic facilitation of rhythmic activity. Brain Res. 1033: 20-7.
  16. Müller M, Mironov SL, Ivannikov MV, Schmidt J, Richter DW. 2005. Mitochondrial organization and motility probed by two-photon microscopy in cultured mouse brainstem neurons. Exp Cell Res. 303:114-27.
  17. Mironov SL, Ivannikov MV, Johansson M. 2005. [Ca2+]i signaling between mitochondria and endoplasmic reticulum in neurons is regulated by microtubules. From mitochondrial permeability transition pore to Ca2+ -induced Ca2+ release. J Biol Chem. 280: 715-21.
  18. Müller M, Mironov SL, Schmidt J, Richter DW (2003). Construction and performance of a custom-built 2-photon laser scanning system. J Phys D 1747-1757.
  19. Mironov SL, Richter DW 2001. Oscillations and hypoxic changes of mitochondrial variables in neurons of the brainstem respiratory centre. J Physiol 533: 227-236.
  20. Haller M, Mironov SL, Richter DW 2001. Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress. J Neurophysiol 86: 412-21.
  21. Haller M, Mironov SL, Karschin A, Richter DW 2001. Dynamic activation of KATP channels in rhythmically active neuron. J Physiol 537:69-81.
  22. Mironov SL, Langohr K, Richter DW 2000. Hyperpolarization-activated current in inspiratory brainstem neurones and its inhibition by hypoxia. Eur J Neurosci 12: 520-526.
  23. Richter DW, Mironov SL, Büsselberg D, Bischof AM, Lalley PM., Wilken B. 2000. Respiratory rhythm generation: Plasticity of a neuronal network. Neuroscientist 6: 188-205.
  24. Mironov SL, Richter DW 2000. Intracellular signalling pathways modulate KATP channels in inspiratory brainstem neurones and their hypoxic activation: Involvement of metabotropic receptors, G-proteins and cytoskeleton. Brain Res 853: 60-67.
  25. Mironov SL, Richter DW 2000. Modulation of L-type Ca channels in inspiratory brainstem neurones: Intracellular signalling pathways and metabotropic glutamate receptors. Brain Res 869: 166-177.
  26. Mironov SL, Langohr K, Richter DW 1999. A1 adenosine receptors modulate respiratory activity of the neonatal mouse via the cAMP-mediated signalling pathway. J Neurophysiol 81, 241-255.
  27. Mironov SL, Langohr K, Richter DW 1999. Cytoskeleton mediates inhibition of the fast Na+ current in respiratory brainstem neurones during hypoxia. Eur J Neurosci 11: 1831-1834.
  28. Mironov SL, Langohr K, Haller M, Richter DW 1998. K+ channels in respiratory neurones of neonatal mice are activated by hypoxia. J. Physiol. 509: 755-766.
  29. Mironov SL, Richter DW 1998. L-type Ca2+ channels in inspiratory neurons and their modulation by hypoxia. J Physiol 512: 75-87.
  30. Mironov SL, Hermann A 1996. Ethanol actions on the mechanisms of Ca2+ mobilization in rat hippocampal cell are mediated by protein kinase C. Brain Res 714: 27-37.
  31. Mironov SL 1995. Plasmalemmal and intracellular Ca2+ pumps as main determinants of slow Ca2+ buffering in rat hippocampal neurones. Neuropharmacology 34: 1123-1132.
  32. Mironov SL 1994. Mechanisms of Ca2+ mobilization from intracellular stores in chick sensory neurons. NeuroReport 5: 445-448.
  33. Mironov SL 1994. Monovalent amidiniums block calcium channels in chick sensory neurons. J. Membrane Biol 141: 131-137.
  34. Mironov SL 1994. Metabotropic ATP receptor in hippocampal and thalamic neurons: Pharmacology and modulation of mechanisms of Ca2+ liberation. Neuropharmacology 33: 1-13.
  35. Mironov SL, Hermann A 1994. Spatial and dye correlation analysis of intracellular Ca2+ distribution. J Bioluminesc Chemiluminesc 9: 233-241.
  36. Mironov SL, Lux HD 1993. NH4Cl-induced inward currents and cytoplasmic Ca2+ transients in chick sensory neurons. NeuroReport 4: 1055-1058.
  37. Mironov SL 1993. Spatiotemporal features of [Ca] transients in neurons. Adv. Exp. Med. Biol. 333: 137-143.
  38. Mironov SL, Usachev YM, Lux HD 1993. Spatial and temporal control of [Ca] transients on chick sensory neurons. Pflügers Arch. 424: 183-191.
  39. Mironov SL, Lux HD 1992. A selective increase of high-threshold Ca current by glutamate in hippocampal cells. Brain Research 580: 341-344.
  40. Mironov SL, Lux HD 1992. Quinacrine blocks high-threshold calcium current in hippocampal neurons. Brit J Pharmacol 106: 751-755.
  41. Mironov SL 1992. Conformational model for ion permeation in membrane channels: A comparison with multi-ion models and applications to Ca channel permeability. Biophysical J 63: 485-496.
  42. Mironov SL 1992. Flash photolysis of caged compounds. In: Electrophysiological Methods for in vitro Studies in Vertebrate Neurobiology. Springer-Verlag, Heidelberg. pp. 139-145.
  43. Mironov SL, Usachev JM 1991. Caffeine affects Ca uptake and Ca release from intracellular stores. Neurosci Lett 123: 200-202.
  44. Mironov SL 1991. Modeling of the Ca diffusion in a cytoplasm. Biol membranes 8: 983-989.
  45. Mironov SL 1991. The mechanism of Ca wave generation by intracellular Ca stores. Biol membranes 8: 989-993.
  46. Mironov SL 1991. Concanavalin A as a tool to change intracellular pH. Trends Neurosci 5: 13.
  47. Mironov SL 1991. A simple non-iterative procedure for fitting of multi-exponential functions. J Neurosci Meth 38: 243-246.
  48. Mironov SL, Lux HD 1991. Cytoplasmic alkalinization increases high-threshold calcium current in chick dorsal root ganglion neurones. Pflügers Arch 419: 138-143.
  49. Mironov SL, Lux HD 1991. Calmodulin antagonists and protein phosphatase inhibitor okadaic acid fasten a 'run-up' of calcium current in hippocampal neurons. Neurosci Lett 133: 175-178.
  50. Usachev YM, Mironov SL 1990. Effects of strontium and barium ions on calcium binding and transport in nerve cells. Neurophysiology 21: 820-825.
  51. Kirischuk SI, Zhukarev VA, Mironov SL. 1990. 2D-analysis of biological microobject images using digital fluorescence microscopy. Biol membranes 7: 399-405.
  52. Belan PV, Mironov SL, Tepikin AV, Osipenko ON 1990. Changes produced in intracellular Ca concentration and transmembrane currents by iontophoretic injection of cAMP in Helix pomatia neurons. Neurophysiology 21: 396-402.
  53. Mironov SL 1990. Theoretical analysis of propagation of [Ca]i wave along the surface of intracellular stores. J Theor Biol 146: 87-97.
  54. Mironov SL, Usachev JM 1990. Sr and Ba transients in isolated snail neurones. Neurosci Lett 112: 184-189.
  55. Sokolov YV, Mironov SL, Rozhmanova OM 1989 Single calcium channels from t-tubular system of skeletal muscle in planar membranes and modulation of their kinetics by 1,4-dihydropyridines. Biol membranes 6: 637-641.
  56. Kostyuk PG, Mironov SL, Belan PV, Tepikin AV 1989. Cytoplasmic free Ca in isolated snail neurons: mechanisms of Ca recovery and Ca release from intracellular stores. J Membrane Biol 110: 11-18.
  57. Mironov SL, Tepikin AV 1988. On the nature of cyclic changes in a cytoplasmic [Ca]. Biol membranes 5: 489-498.
  58. Mironov SL 1988. A diffusional model for Ca channel inactivation. Neurophysiology 20: 463-465.
  59. Nalivaiko ED, Mironov SL 1988. The effects of concanavalin A on intracellular Ca concentration and transmembrane potential of rabbit lymphocytes. Physiol J 34: 84-86
  60. Mironov SL 1988. Modulation of ionic selectivity of neuronal Ca channels. In: Ca and Ion Channel Modulation. Ed A Grinnell et al. Plenum Press. pp. 43-55.
  61. Mironov SL, Dolgaya EV 1987. Microelectrophoresis and fluorescence resonance energy transfer sudies of surface charge in murine neuroblastoma cells. Bioelectrochem Bioenerg 17: 429-439.
  62. Belan PV, Tepikin AV, Mironov SL 1987. Changes in intracellular Ca in isolated snail neurons as revealed by chlorotetracycline. Neurophysiology 19: 686-687.
  63. Belan PV, Dolgaya EV, Tepikin AV, Mironov SL 1987. The dependence of the surface potential of neuroblastoma cells on the phase of the cell cycle. Neurophysiology 19: 130-132.
  64. Tepikin AV, Mironov SL, Belan PV 1987. Changes in cytoplasmic Ca in isolated snail neurons as revealed by fuorescence probe fura-2. Biol membranes 4: 785-792.
  65. Kostyuk PG, Tepikin AV, Mironov SL, Belan PV 1987. The mechanisms of cytoplasmic Ca changes in snail neurons involving intracellular Ca stores. Biol membranes 4: 793-800.
  66. Chanturia AV, Mironov SL, Sokolov JV 1986. Energy profile of channels formed by lathrotoxin in lipid bilayers. Ukr Biochem J 58: 48-57.
  67. Mironov SL, Sokolov YV, Chanturia AN, Lishko VN 1986. Channels produced by spider venoms in lipid bilayer membranes. Biochim Biophys Acta 862: 185-198.
  68. Kostyuk PG, Mironov SL 1986. Kinetic behaviour of a model of a calcium channel with 2 conformational states Neurophysiology 18: 705-707.
  69. Dolgaya EV, Mironov SL, Pogorelaya NC 1985. Surface charge of neuroblastoma cells and its changes during cell growth and differentiation. Neurophysiology 17: 168-174.
  70. Dolgaya EV, Mironov SL 1985. The effect of divalent cations and lyotropic anions on the surface potential of rat dorsal root ganglion neurones. Biol membranes 2: 934-939.
  71. Mironov SL, Tepikin AV, Grischenko AV 1985. Two Ca channels in the somatic membrane of molluscan neurons. Neurophysiology 17: 562-571.
  72. Kostyuk PG, Mironov SL 1985. Theoretical models for Ca channels in nerve cells. In: Water and ions in biological systems. Plenum Press. NY. pp. 17-26.
  73. Mironov SL, Dolgaya EV 1985. Surface charge of mammalian neurones as revealed by a microelectrophoresis. J Membrane Biol 98: 197-202.
  74. Mironov SL 1984. Calculation of electron coupled states in the electric dipole field by the MO LCAO method. J Phys Chem 58: 2861-2862 1984
  75. Mironov SL 1984. Firing mechanisms in mammalian neurones. Neurophysiology 16: 347-353.
  76. Mironov SL 1984. Is there a carboxylic group in the selectivity filter of the voltage-sensitive sodium channel? Bioelectrochem Bioenerg 12: 731-735.
  77. Dolgaya EV, Mironov SL 1984. Microelectrophoretic study of the surface of rat DRG neurones. Neurophysiology 16: 176-182.
  78. Mironov SL 1983. Pacemaker mechanisms in snail neurons. Neurophysiology 14: 899-905.
  79. Kostyuk PG, Mironov SL, Shuba YM 1983. Na/Ca permeability of voltage-sensitive Ca channels is controlled by external micromolar Ca. Neurophysiology 76: 83-93.
  80. Mironov SL 1983. Slow wave membrane potential oscillations in mollusc neurons. Neuroscience 10: 899-905.
  81. Kostyuk PG, Mironov SL, Shuba YM 1983. Two ion-selecting filters in Ca channel of mollusc neurons. J Membrane Biol 76: 83-93.
  82. Mironov SL 1983. Comparison of ion selectivity filters in Na and Ca channels. Proc Acad Sci USSR 258: 358-362.
  83. Mironov SL 1982. Mechanisms of Ca channel functioning in rat DRG neurones. Neurophysiology 14: 204-206.
  84. Mironov SL 1982. Determination of the exponent of ion current activation for the Hodgkin - Huxley model. Neurophysiology 14: 207-208.
  85. Mironov SL 1982. MO LCAO calculations of bound state of an electron in the dipole field. J Phys Chem 48: 2861-2863
  86. Kostyuk PG, Mironov SL 1982. Theoretical description of Ca channels in rat DRG neurones. Neurophysiology 14: 94-101.
  87. Mironov SL 1982. The conduction band for excess electron in proteins. Theor Exp Chimia 17: 327-336.
  88. Kostyuk PG, Mironov SL, Doroshenko PA, Ponomarev VN 1982. Surface charges on the outer surface of mollusc neurons. J Membrane Biol 70: 171-179.
  89. Kostyuk PG, Mironov SL, Doroshenko PA 1982. Energy profile of Ca channel in the neuronal membrane. J Membrane Biol 70: 181-189.
  90. Kostyuk PG, Mironov SL, Doroshenko PA 1981. Application of three-barrier model for description of Ca channel in snail neurones. Neurophysiology 12: 485-492.
  91. Mironov SL 1980. Processes of electron transport on SIO2 surface. J Phys Chem 54: 1283-1284.
  92. Mironov SL 1980. The bound state of excess electron in proteins. Theor Exp Chem. 16: 1124-1135.
  93. Mironov SL, Gorlov JI, Tschuiko AA 1980. Electrostatic potential and absorption properties of silica dioxide. Ukr. Phys. J. 22: 1251-1260.
  94. Kononenko NI, Mironov SL 1980. The effects of intracellular cAMP injection on the electric characteristics of snail neurons. Neurophysiology 12: 485-492.
  95. Mironov SL, Doroshenko PA, Kostyuk PG 1980. Ion selectivity of calcium channel in the surface membrane of snail neurons. Proc Acad Sci USSR 253: 978-981.
  96. Mironov SL, Ukrainskii II 1979. Madelung energy and electronic structure of TTF-TCNQ crystals. Ukr Phys J 22: 1385-1352.
  97. Mironov SL, Ukrainskii II 1979. On the nature of the conduction band in polypeptides. Theor Exp Chem. 15: 144-151
  98. Mironov SL 1979. A theoretical study of electronic structure of polyglicine. Theor Exp Chem. 15: 138-143.
  99. Mironov SL, Tkachenko KI, Tschuiko AA 1978. Band structure, photo- and X-ray-electron spectra of of silica dioxide. Theor Exp Chem 14: 538-542.
  100. Mironov SL, Tkachenko KI, Tschuiko AA 1978. On the nature of σ-d(π) conjugation in of silica halides.Theor Exp Chem 14: 37-40.